REVIEW

Rolul microbiotei intestinale în sindromul de colon iritabil

 The role of intestinal microbiota in irritable bowel syndrome

First published: 28 iunie 2024

Editorial Group: MEDICHUB MEDIA

DOI: 10.26416/JourNutri.2.2.2024.9759

Abstract

Recent studies have shown a close connection between the composition of the microbiome and the presence of con­­di­tions such as irritable bowel syndrome (IBS). The main objective of this study is to identify the existing evi­dence in the literature in support of this association. The method­ology included an exhaustive search of scientific databases for relevant studies, followed by a critical ana­ly­sis of them. The results showed that, although there are studies sug­ges­ting a link between changes in gut mi­cro­bio­ta and im­prove­ment in SCI symptoms, the evi­dence is not yet suf­fi­ciently conclusive. This research falls within a par­ti­cu­larly important context, marked by a significant increase in the incidence of the previously men­tioned pathology. How­ever, further clinical trials are needed to validate the efficacy and mechanisms involved in this therapeutic strategy.
 

Keywords
microbiome, inflammation, syndrome, irritable bowel 

Rezumat

Studiile recente au evidenţiat o strânsă legătură între com­po­zi­ţia microbiomului şi prezenţa unor afecţiuni precum sin­­dro­­mul de colon iritabil. Obiectivul principal al acestui studiu este de a identifica dovezile existente în literatura de specialitate în sprijinul acestei asocieri. Metodologia a inclus o căutare ex­ha­us­ti­vă în bazele de date ştiinţifice pentru studii relevante, ur­ma­tă de o analiză critică a acestora. Rezultatele au arătat că, deşi există studii care sugerează o legătură între modificările mi­cro­bio­tei intestinale şi ameliorarea simptomelor sindromului de colon iritabil, dovezile nu sunt încă suficient de concludente. Aceas­tă cercetare se încadrează într-un context deosebit de im­por­tant, marcat de o creştere semnificativă a incidenţei patolo­giei menţionate anterior. Cu toate acestea, sunt necesare studii cli­ni­ce suplimentare pentru a valida eficacitatea şi mecanismele im­pli­ca­te în această strategie terapeutică.

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