RUBRICA SPECIALISTULUI

Intoleranţa la histamină

 Histamine intolerance

First published: 31 octombrie 2023

Editorial Group: MEDICHUB MEDIA

DOI: 10.26416/Aler.7.3.2023.8791

Abstract

Histamine intolerance, also referred to as enteral histaminosis or sensitivity to dietary histamine, is a disorder associated with an impaired ability to metabolize ingested histamine that was described at the beginning of the 21st century. Although interest in histamine intolerance has considerably grown in recent years, more scientific evidence is still required to help define, diagnose and clinically manage this condition. This article will provide an updated review on histamine intolerance, mainly focusing on its etiology and the existing diagnostic, differential diagnoses and treatment strategies.
 

Keywords
histamine intolerance, histamine, diamine oxidase, DAO, low-histamine diet, probiotics, food intolerance

Rezumat

Intoleranţa la histamină, denumită şi histaminoză enterală sau sensibilitate la alimente care conţin histamină, este o tulburare asociată cu o capacitate deficitară de a metaboliza histamina ingerată, care a fost descrisă la începutul secolului XXI. Deşi interesul pentru intoleranţa la histamină a crescut considerabil în ultimii ani, sunt încă necesare mai multe dovezi ştiinţifice pentru a ajuta la definirea, diagnosticarea şi gestionarea clinică a acestei afecţiuni. Articolul de faţă prezintă o analiză actualizată a intoleranţei la histamină, concentrându-se în principal pe etiologia acesteia şi pe strategiile de diagnostic, diagnostic diferenţial şi tratament existente.
 

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