This edition of our journal begins at the obstetrics section with a challenging obstetrical pathology – placenta praevia and abnormally invasive placenta, highlighting a retrospective study from the University Emergency Hospital Bucharest over a five-year period, with the aim of evaluating the therapeutic methods applied for placenta praevia with abnormal adherence.

The next paper brings to the front a literature review about fetomaternal hemorrahage, which is a rare but important condition to consider in the diagnosis of fetal distress.

In the gynecology section, it is presented the uterine carcinosarcoma, a biphasic tumor with an epithelial and mesenchymal component, that has been included in the last WHO classification of female genital tumors in the endometrial carcinoma category. A retrospective study was conducted, including hysterectomy specimens with the diagnosis of carcinosarcoma.

Breast cancer represents the most common cancer worldwide, being the second deadliest cancer in women. There is no doubt regarding the importance of breast cancer screening, mammography representing the primary imaging technique used to detect suspicious lesion for breast cancer. In the following article, the authors want to demonstrate that patients with breast tissue augmentation need a routine screening mammography in order to evaluate the native breast tissue. The indications for breast cancer screening are the same as in women without implants, the only difference being that women with breast implants should be approached dif­ferently, from a clinical point of view.

Moving on, the impact of hysterectomy for benign conditions on patients’ life is major, sexual life having a significant importance in a woman’s life during premenopause and beyond. A study was carried out, showing that the low quality of se­x­ual life can lead to changes in behavior, in the perception of her own body, to lower self-esteem and, subsequently, to a lower quality of life, but it is not significantly affected by hysterectomy.

The following paper emphasizes a very contradictory topic: “Antibiother­apy in a tertiary neonatal care unit – use or abuse?” This retrospective study, that evaluated the use of antibiotics in a group of 241 newborns, was held in the “Bucur” Maternity, Bucharest, Romania, between 2018 and 2020, observing a tendency to overmedication in this age category, with possible risks, such as adverse reactions and the selection of resistant germs, that do not always outweigh the benefits. More regulations regarding the indications of antibiotic treatment in newborns are needed in order to avoid possible risks, both at the individual and the community level.

Another important aspect that we are proud to mention is that we reached Milestone 40, as the number of publications of our journal.

Last but not least, we would like to invite you to two major events: the 5th National Congress of the East-European Endometriosis and Infertility Society, and the 8th National Conference of the Romanian HPV Society, which will take place between 15 and 17 June 2023, at Kronwell Hotel, Braşov.